PaPaS News
Expect analgesic failure; pursue analgesic success
One of our Editors, Professor Andrew Moore, has now published, 'Expect analgesic failure; pursue analgesic success' (BMJ 2013;346:f2690) in the British Medical Journal. You can see the full article here.
'Most analgesic drugs work well but in only a small percentage of people. Andrew Moore and colleagues argue that we need to move away from a focus on average response and seek out what works for each patient.'
The Consumer and Developing Country Stipends Committees are pleased to announce that stipends application is now open for the 21st Cochrane Colloquium, 19-23 Sep 2013, Québec City, Canada. A limited number of stipends to cover travel, accommodation and registration to attend the Colloquium are available for contributors to The Cochrane Collaboration who are consumers or residents of developing countries. Detailed information on criteria and how to apply can be found on http://colloquium.cochrane.org/colloquium-stipends.
Deadline for submitting applications is Thursday 16 May 2013.
For any queries please contact Juliane Ried at consumerstipends@cochrane.org or dcstipends@cochrane.org.
Evidently Cochrane: a blog
Our colleagues at the UK Cochrane Centre have created a blog, sharing and summarising the latest Cochrane reviews.
Methodological Expectations of Cochrane Intervention Reviews (MECIR)
For information about how this affects PaPaS authors and contributors directly, please contact Anna Hobson, Managing Editor, at anna.hobson@ndcn.ox.ac.uk.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Amitriptyline for neuropathic pain and fibromyalgia in adults. Cochrane Database of Systematic Reviews 2012, Issue 12. Art. No.: CD008242. DOI: 10.1002/14651858.CD008242.pub2. Faculty of 1000 Recommended
The following paper has also been recommended here:
Moore, R. A., Straube, S. and Aldington, D. (2013), Pain measures and cut-offs – ‘no worse than mild pain’ as a simple, universal outcome. Anaesthesia. doi: 10.1111/anae.12148. Faculty of 1000 Recommended
PaPaS in the news
BBC News
NICE releases new pain relief guidelinesMorphine and pain control
Telegraph
Patients left in great pain because doctors are unsure about using strong drugs, NICE warns
London Evening Standard
New advice on opium-based drugs
Yorkshire Evening Post
Opioids 'key in palliative care'
Other news
Your Health Net website launched
The Cochrane Consumers and Communication review group have been involved with a project to launch a website to help people be more actively engaged in healthcare decisions they make. Take a look: http://navigatingeffectivetreatments.org.au/. We've added a link to this website to our consumers, authors and referee information that we routinely send out.
Summary of Findings document
Please take a look at our 'Summary of Findings document', available under 'PaPaS documents'. This document was drawn up by our Editors to help authors write a Summary of Findings table and can be used alongside Chapter 11 of the Cochrane Handbook.
Single dose oral analgesics for acute postoperative pain in adults, an overview review
In September 2011, PaPaS sees the publication of its first overview of reviews. This overview brings together the results from 35 separate Cochrane reviews of single dose analgesics in acute postoperative pain, with 38 different drug or drug combinations, at various doses, tested in about 45,000 patients in 350 clinical trials.The primary outcome was number needed to treat for at least 50% of maximum pain relief over four to six hours, with secondary outcomes including the proportion of individuals achieving this level of response, and time to use of rescue medication. Comparisons were made with placebo, and results presented in rank order of efficacy, with further consideration given to the quantity of evidence and how confidant we can be in the results.This analgesic league table should help commissioners, prescribers and patients to make treatment decisions based on robust efficacy data together with local availability, and tailored to the individual patient according to need (e.g. long duration of action) and tolerability.
Please go to The Cochrane Library homepage to read the full review: www.thecochranelibrary.com/
The Cochrane Library Impact Factor for 2011
The 2011 Impact Factor has now been released and is 5.912 for The Cochrane Collaboration as a whole, and for the PaPaS review group itself it is 5.787 which makes us the highest impact pain journal in circulation!
Please visit the Cochrane Editorial Unit site for information on the Collaboration's 2011 impact factor.
PaPaS Author and Peer Referee Guidance
Please have a look at our new guidance to support our authors and referees in writing and assessing reviews. This document has undergone significant consultation and we expect authors to justify any diversions from the guidance. This document can be found on the following link or by going to the 'PaPaS documents' section of our website. PaPaS author and referee guidance. Have a read and let us know what you think.
Laxatives or methylnaltrexone for the management of constipation in palliative care patients
Take a look at one of our first Cochrane Journal Clubs: http://bit.ly/gpoG8c
The Cochrane Collaboration Annual report: how much The Cochrane Colloboration has done over the last couple of years
Take a look at The Cochrane Collaboration annual report:
www.cochrane.org/sites/default/files/uploads/Annual%20Report%202009-10_The%20Cochrane%20Collaboration.pdf
Monthly publications
Review groups are now publishing protocols and reviews in The Cochrane Library on a monthly basis. Deadlines for submitting drafts or completed reviews can be found in the 'Resources for review authors' section.
We are always on the look out for peer referees, consumers, handsearchers, translators and those interested in offering statistical and methodological support, if you’d be interested in this, do get in contact with Anna Hobson.
Please see our 'module text' on The Cochrane Library to see a list of our current published protocols, reviews and review updates as well as titles in progress and due for publication soon: http://onlinelibrary.wiley.com/o/cochrane/clabout/articles/SYMPT/frame.html
Publications
2012 publications
Acute- Interventions for the symptoms and signs resulting from jellyfish stings [Richard McGee] - Protocol Issue 3, 2012
- Milnacipran for neuropathic pain and fibromyalgia in adults [Sheena Derry] - Review Issue 3, 2012
- Nalbuphine for postoperative pain in children [Alexander Schnabel] - Protocol - Issue 1
- Single dose oral celecoxib for acute postoperative pain in adults [Sheena Derry] - Review Update Issue 3, 2012
- Tramadol for postoperative pain in children [Alexander Schnabel] - Protocol - Issue 1
- Clonazepam for neuropathic pain and fibromyalgia in adults [Ruth Corrigan] - Review Issue 5, 2012
- Phenytoin for neuropathic pain and fibromyalgia in adults [Fraser Birse] - Review Issue 5, 2012
- Psychological interventions for acute pain after open heart surgery in adults [Susan Tefikow] - Protocol Issue 7, 2012
- Combination pharmacotherapy for the treatment of neuropathic pain in adults - [Ian Gilron] - Luis Enrique Chaparr - Review Issue 7, 2012
- Buprenorphine for treating cancer pain [Cho-Min Naing] - Protocol - Issue 1
- Caffeine as an analgesic adjuvant for acute pain in adults [Christopher Derry] - Review Issue 3, 2012
- Tapentadol for chronic musculoskeletal pain in adults [João Santos] - Protocol Issue 6, 2012
- Diclofenac with or without an antiemetic for acute migraine headaches in adults [Sheena Derry] - Review Issue 2, 2012
- Sumatriptan (intranasal route of administration) for acute migraine attacks in adults [Christopher Derry] - Review Issue 2, 2012
- Sumatriptan (oral route of administration) for acute migraine attacks in adults [Christoper Derry] - Review Issue 2, 2012
- Sumatriptan (rectal route of administration) for acute migraine attacks in adults [Christopher Derry] - Review Issue 2, 2012
- Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults [Christopher Derry] - Review Issue 2, 2012
- Advance care-planning for end-of-life care [Dirk Houttekier] - Protocol Issue 2, 2012
- Aromatherapy and massage for symptom relief in patients with cancer [Ein-Soon Shin] - Protocol Issue 6, 2012
- Blood transfusions for anaemia in patients with advanced cancer [Nancy Preston] - Review Issue 2, 2012
- Calcitonin for metastatic bone pain [Maria Martinez-Zapata] - Review Update Issue 2, 2012
- Interventions for fatigue and weight loss in adults with advanced progressive illness - an overview [Cathy Payne] - Review Issue 1
- Patient positioning (mobilisation) and bracing for pain relief and spinal stability in metastatic spinal cord compression in adults [Siew Hwa Lee] - Review Issue 3, 2012
- Psychological interventions for parents of children and adolescents with chronic illness [Christopher Eccleston] - Protocol Issue 2, 2012
- Self management interventions for breathlessness in adult cancer patients [Doris Howell] - Protocol Issue 2, 2012
- Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults [Adam Hurlow] - Review Update Issue 3, 2012
- Spiritual and religious interventions for well-being of adults in the terminal phase of disease [Bridget Candy] - Review Issue 5 2012
2011 publications
Acute- Caffeine as an analgesic adjuvant for acute pain in adults [Christopher Derry] - Protocol - Issue 8
- Music for pain relief [David Bradshaw] - Protocol (update of published review) - Issue 9
- Pain relief for the removal of femoral sheath removal after percutaneous coronary intervention [Cynthia Wensley] - Update Review - Issue 9
- Single-dose intra-articular morphine for pain control after knee arthroscopy [Zui Zou] - Protocol Issue 1
- Single dose oral fenoprofen for acute postoperative pain in adults [Maria Traa] - Full Review - Issue 2
- Single dose oral mefenamic acid for acute postoperative pain in adults [Rachael Moll] - Full Review - Issue 3
- Single dose oral analgesics for acute postoperative pain in adults [Andrew Moore] - Overview Review - Issue 9
- Transcutaneous electrical nerve stimulation for acute pain [Deirdre Walsh] - Update Review - Issue 8
- Acupuncture for neuropathic pain in adults [Ellen Wang] - Protocol - Issue 2
- Carbamazapine for acute and chronic pain in adults [Phil Wiffen] - Updated Review - Issue 1
- Clonazepam for neuropathic pain and fibromyalgia in adults [Ruth Corrigan] - protocol - Issue 12
- Combination pharmacotherapy for the treatment of neuropathic pain in adults [Ian Gilron] Protocol - Issue 1
- Gabapentin for chronic neuropathic pain and fibromyalgia in adults [Andrew Moore] - New Review - Issue 3
- Interventions for treating pain and disability in adults with complex regional pain syndrome [Neil O'Connell] - Protocol - Issue 11
- Lamotrigine for acute and chronic pain [Phil Wiffen] - Updated Review - Issue 2
- Music for pain relief [David Bradshaw] - Protocol (update of published review) - Issue 9
- Pharmacologic interventions for treating phantom limb pain [M Jen Alviar] - Protocol - Issue 12
- Phenytoin for neuropathic pain and fibromyalgia in adults [Fraser Birse] - Protocol - Issue 12
- Posture and fluids for prevention of post-dural puncture headache [Ingrid Arevalo-Rodriguez] - Protocol - Issue 7
- Valproic acid and sodium valproate for neuropathic pain and fibromyalgia [Dipender Gill] - Protocol - Issue 7
- Aspirin for acute episodic tension-type headache in adults [Girish Kulkarni] - Protocol - Issue 12
- Drug therapy for treating post-dural puncture headache - [Xavier Basurto Ona] - Review - Issue 5
- Naproxen with or without an antiemetic for acute migraine headaches in adults [Sheena Derry] - Issue 11
- Paracetamol (acetaminophen) for acute episodic tension-type headache in adults [Girish Rao] - Protocol - Issue 12
- Sumatriptan (all routes of administration) for acute migraine headaches in adults: an overview of Cochrane reviews [Andrew Moore] - Protocol
- Acupuncture for cancer pain in adults [Carole Paley] - Full Review - Issue 1
- Blood transfusions for anaemia in patients with advanced cancer [Nancy Preston] - Protocol - Issue 2
- Celiac plexus block for pancreatic cancer pain in adults [Paolo Aricidiacono] - Full Review - Issue 3
- Levomepromazine for nausea and vomiting in palliative care [Emily Darvill] - Protocol - Issue 11
- Interventions for improving palliative care for older people living in nursing care homes [Sue Hall] - Full Review - Issue 3
- Laxatives or methylnaltrexone for the management of constipation in palliative care patients [Bridget Candy - Update Review - Issue 1
- Medically assisted hydration for adult palliative care patients [Phillip Good] - Updated Review - Issue 3
- Multidisciplinary care for follow-up after primary brain tumour treatment [Fary Khan] - Protocol - Issue 12
- Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease [Matthew Maddocks] - Issue 11
- Radioisotopes for metastatic bone pain [Marta Roque] - Updated Review - Issue 7
2011 publications
- Analgesics for postoperative pain after tonsillectomy and adenoidectomy in children [O'Mathuna] - Updated Protocol
- Attention-based interventions for the management of pain and distress in young children (3-12 years) with burn injuries [Kate Miller] - Protocol
- Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery [Shona Charlton] - Full Review
- Single dose oral analgesics for acute postoperative pain in adults - OVERVIEW [Andrew Moore] - Protocol
- Single dose oral codeine, as a single agent, for acute postoperative pain in adults [Sheena Derry] - Full Review
- Single dose oral diflunisal for acute postoperative pain in adults [Jack O Wasey] - Full Review
- Single dose dipyrone for acute post operative pain [Sheena Derry] - Updated Review
- Single dose oral gabapentin for established acute postoperative pain in adults [Sebastian Straube] - Full Review
- Single-dose lumiracoxib for postoperative pain in adults [Yvonne Roy] - Updated Review
- Sweet-tasting solutions for needle-related procedural pain in infants [Manal Kassab] - Protocol
- Sweet-tasting solutions for needle-related procedural pain in children aged one to 16 years [Denise Harrison] - Protocol
- Topical NSAIDS for acute pain in adults [Thomas Massey] - Full Review
- Single dose tramadol for acute postoperative pain in adults [Elisa Cazue Sudo] - Protocol
- Amitriptyline for neuropathic pain and fibromyalgia in adults [R Andrew Moore] - Protocol
- Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome [Sebastian Staube] - Updated Review
- Long term opioid management for chronic noncancer pain [Meredith Noble] - Full Review
- Milnacipran for neuropathic pain and fibromyalgia in adults [Sheena Derry] - Protocol
- Non-invasive brain stimulation techniques for chronic pain [Neil O'Connell] - Full Review
- Overview of reviews: Topical analgesics for acute and chronic pain in adults [Andrew Moore] - Protocol
- Pharmacotherapy for the prevention of chronic pain after surgery in adults [Ian Gilron] - Protocol
- Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults [Leica Claydon] - Protocol
- Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults [Matthew Mulvey] - Full Review
- Vitamin D for the treatment of chronic painful conditions in adults [Sebastian Straube] - Full Review
- Aspirin with or without an antiemetic for acute migraine headaches in adults [Varo Kirthi] - Full Review
- Diclofenac with or without an antiemetic for acute migraine headaches in adults [Sheena Derry] - Protocol
- Eletriptan for acute migraine headaches in adults [Sheena Derry] - Protocol
- Epidural blood patching for preventing and treating post-dural puncture headache [Boonmak P] - Updated Review
- Ibuprofen with or without an antiemetic for acute migraine headaches in adults [Roy Rabbie] - Full Review
- Naratriptan for acute migraine headaches in adults [Sheena Derry] - Protocol
- Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults [Sheena Derry] - Full Review
- Rizatriptan for acute migraine headaches in adults [Rebecca Ling] - Protocol
- Sumatriptan for acute migraine headaches in adults [Sheena Derry] - Protocol
- Sumatriptan plus naproxen for acute migraine headaches in adults [Simon Law] - Protocol
- Triptans for acute cluster headache [Simon Law] - Full Review
- Zolmitriptan for acute migraine headaches in adults [Sheena Derry] - Protocol
- Benzodiazepines for the relief of breathlessness in advanced malignant and non-malignant diseases in adults [Steffen Simon] - Full Review
- Droperidol for treatment of nausea and vomiting in palliative care patients [Saskie Dorman] - Full Review
- Drug therapy for the management of cancer-related fatigue [Ollie Minton] - Updated Review
- End-of-life care pathways for improving outcomes in caring for the dying [Raymond Chan] - Full Review
- Interventions for cough in cancer [Alex Molassiotis] - Full Review
- Overview of Reviews: Interventions for fatigue and weight loss in adults with advanced progressive illness [Cathy Payne] - Protocol
- Interventions for noisy breathing in patients near to death [Bee Wee] - Updated Review
- Interventions for treating persistent and intractable hiccups in adults [Emilia Moretto] - Protocol
- Laxatives for the management of constipation in palliative care patients [Bridget Candy] - Update Review
- Long term opioid management for chronic noncancer pain [Meredith Noble] - Full Review
- Metoclopramide for chronic nausea in adult palliative care patients with advanced cancer [Katherine Clark] - Protocol
- Music therapy for end-of-life care [Joke Bradt] - Full Review
- Pharmacological interventions for pruritus in adult palliative care patients [Carola Xander] - Protocol
- Pharmacological treatments for fatigue associated with palliative care [Vera Peuckmann] - Full Review
- Serotonin receptor antagonists for highly emetogenic chemotherapy in adults [Atto Billio] - Full Review
- Supportive care for patients with gastrointestinal cancer [Nisar Ahmed] - Updated Review
The Top 10!
The top 10 published PaPaS reviews accessed in The Cochrane Library for 2008 were:
- Exercise for the management of cancer-related fatigue in adults [Fiona Cramp] - Full Review
- Antidepressants for neuropathic pain [Tiina Saarto] - Updated Review
- Non-pharmacological interventions for breathlessness in advanced stages of malignant disease [Claudia Bausewein] - Full review
- Patient controlled opiod analgesia versus conventional opioid analgesia for post opertaive pain [Jana Hudcova] - Full Review
- Aromatherapy and massage for symptom relief in patients with cancer [Deborah Fellowes]
- Gabapentin for acute neuropathic pain
- Music for pain relief [Soledad Cepeda] - Full Review
- Laxatives for the management of constipation in palliative care patients [Bridget Candy] - Update Review
- Non-invasive physical treatments for chronic/recurrent headache [Gert Brønfort] - Full Review
- Transcutaneous electrical nerve stimulation (TENS) for chronic pain [Kelechi Nnoaham] - Updated Review
...and for 2009
- Acupuncture for tension-type headache [Klaus Linde] - Updated Review
- Acupuncture for migraine prophylaxis [Klaus Linde] - Updated Review
- Non-pharmacological interventions for breathlessness in advanced stages of malignant and non-malignant diseases [Claudia Bausewein] - Full Review
- Exercise for the management of cancer-related fatigue in adults [Fiona cramp] - Full Review
- Antidepressants for neuropathic pain [Tiina Saarto] - Updated Review
- Patient controlled opioid analgesia versus conventional opioid analgesia for postoperative pain [Jana Hudcova] - Full Review
- Music for pain relief [Soledad Cepeda] - Full Review
- Pregabalin for acute and chronic pain in adults [Andrew Moore] - Full Review
- Transcutaneous electrical nerve stimulation (TENS) for chronic pain [Kelechi Nnoaham] - Updated Review
- Gabapentin for acute and chronic pain [Phillip Wiffen]



